BDBM50025154 3-(4-Amino-phenyl)-pyrrolidine-2,5-dione::CHEMBL148903

SMILES Nc1ccc(cc1)C1CC(=O)NC1=O

InChI Key InChIKey=AFLGSUFOCCZEEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50025154   

TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025154(3-(4-Amino-phenyl)-pyrrolidine-2,5-dione | CHEMBL1...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025154(3-(4-Amino-phenyl)-pyrrolidine-2,5-dione | CHEMBL1...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed