BDBM50025152 3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione::CHEMBL151212

SMILES CCC1(CC(=O)NC1=O)c1ccc(N)cc1

InChI Key InChIKey=QPJZAHJMZUCFMF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025152   

TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025152(3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione |...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025152(3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione |...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025152(3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione |...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed