BDBM50024592 (S)-1-Ammonium-2-phenyl-ethanephosphonic acid anion::CHEMBL289264

SMILES [NH3+][C@H](Cc1ccccc1)P(O)([O-])=O

InChI Key InChIKey=FQCNOURLMNHAQN-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50024592   

TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataIC50: 2.23E+5nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataIC50: 1.39E+5nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataKi:  420nMAssay Description:Inhibition of leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataKi:  1.54E+4nMAssay Description:Compound was tested for inhibition of Leucine aminopeptidase isolated from porcine kidney; Inhibitor exhibits slow-binding behavior(k on <=1000Me-1Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed