BDBM50024538 CHEMBL3330490

SMILES [H][C@@]12CCc3cc(ccc3N1C(=O)O[C@H]2CNC(=O)c1ccc(Cl)s1)N1CCOCC1=O

InChI Key InChIKey=DWIJIDWSULQVIV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50024538   

TargetProthrombin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 2a using L-pyro-Glu-Pro-ArgpNA, S-2366 chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 7a using S-2366 chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 9a using CH3SO2-(D)CHG Gly-Arg-pNA, Biophen-CS51 chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human trypsin using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 11a using S-2366 chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50024538(CHEMBL3330490)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed