BDBM50024095 (R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic acid::CHEMBL349404

SMILES OC(=O)CC(=O)N[C@H](CS)Cc1ccccc1

InChI Key InChIKey=REPVVNYZORKKPQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024095   

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50024095((R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic ...)
Affinity DataIC50: 2.30nMAssay Description:Concentration for 50% inhibition of activity of rat kidney enkephalinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50024095((R) N-(1-Mercaptomethyl-2-phenyl-ethyl)-malonamic ...)
Affinity DataKi:  210nMAssay Description:Inhibition of NEP 24.11 (unknown origin) by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed