BDBM50023901 2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid(8-deaza-10-methylfolate)::CHEMBL158790

SMILES CN(Cc1ccc2nc(N)[nH]c(=O)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=IMGJLQDFQCFWQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023901   

TargetThymidylate synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023901(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Ability to inhibit thymidylate synthase derived from human leukemia K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed