BDBM50023710 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-4-sulfo-butyric acid::CHEMBL281936

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCS(O)(=O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=ZLLDSRTXPHYVLX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023710   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023710(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023710(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataKi:  5.90E+4nMAssay Description:Compound was evaluated for the binding affinity to mouse liver folyl polyglutamate synthetase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed