BDBM50023420 CHEMBL3327329

SMILES OC(=O)CNCCCOc1cc(ccc1OC(F)F)C(=O)Nc1c(Cl)cncc1Cl

InChI Key InChIKey=FNNAAFIIFUBNDP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023420   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Amakem

Curated by ChEMBL

LigandBDBM50023420(CHEMBL3327329)Copy SMILESCopy InChI

Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Amakem

Curated by ChEMBL

LigandBDBM50023420(CHEMBL3327329)Copy SMILESCopy InChI

Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL