BDBM50023415 CHEMBL3327324

SMILES OCCC(NCCCCOc1cc(ccc1OC(F)F)C(=O)Nc1c(Cl)cncc1Cl)C(O)=O

InChI Key InChIKey=MRLBVOBMAVAAQH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023415   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Amakem

Curated by ChEMBL

LigandBDBM50023415(CHEMBL3327324)Copy SMILESCopy InChI

Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Amakem

Curated by ChEMBL

LigandBDBM50023415(CHEMBL3327324)Copy SMILESCopy InChI

Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL