BDBM50023042 CHEMBL3144128::{1-[1-(2-Hydroxy-1-isobutyl-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-naphthalen-2-yl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)CC[C@@H](O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)OC(C)(C)C

InChI Key InChIKey=HMHDZBAQEVCMQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023042   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023042({1-[1-(2-Hydroxy-1-isobutyl-5-methyl-hexylcarbamoy...)
Affinity DataIC50: 600nMAssay Description:The compound was tested for inhibition of human renal renin at the pH optimum 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed