BDBM50023031 CHEMBL3144129::{1-[1-(2-Hydroxy-1-isobutyl-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-naphthalen-1-yl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)CC[C@@H](O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OC(C)(C)C

InChI Key InChIKey=KHWUUKOCPOUZAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023031   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50023031({1-[1-(2-Hydroxy-1-isobutyl-5-methyl-hexylcarbamoy...)
Affinity DataIC50: 150nMAssay Description:The compound was tested for inhibition of human renal renin at the pH optimum 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed