BDBM50022801 CHEMBL5274026

SMILES Nc1cccc(F)c1CN(CCC1CCS(=O)(=O)CC1)C(=O)c1cc(n[nH]1)C(F)(F)F

InChI Key InChIKey=GASMZUDGPKMAEI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022801   

TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research Ahmedabad

Curated by ChEMBL
LigandPNGBDBM50022801(CHEMBL5274026)
Affinity DataEC50:  7.10nMAssay Description:Activation of PKM2 (unknown origin) in presence of sorafenibMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
National Institute of Pharmaceutical Education and Research Ahmedabad

Curated by ChEMBL
LigandPNGBDBM50022801(CHEMBL5274026)
Affinity DataEC50:  50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed