BDBM50022781 (EXP-561)4-Phenyl-bicyclo[2.2.2]oct-1-ylamine::4-Phenyl-bicyclo[2.2.2]oct-1-ylamine::CHEMBL288524

SMILES NC12CCC(CC1)(CC2)c1ccccc1

InChI Key InChIKey=JXMVQBDHMBOHDH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50022781   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50022781((EXP-561)4-Phenyl-bicyclo[2.2.2]oct-1-ylamine | 4-...)
Affinity DataKi:  83nMAssay Description:Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022781((EXP-561)4-Phenyl-bicyclo[2.2.2]oct-1-ylamine | 4-...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022781((EXP-561)4-Phenyl-bicyclo[2.2.2]oct-1-ylamine | 4-...)
Affinity DataKi:  5.10E+4nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed