BDBM50022747 2-(3-Amino-2-hydroxy-4-phenyl-thiobutyrylamino)-4-methyl-pentanoic acid; TFA::CHEMBL304141::CHEMBL68979

SMILES CC(C)C[C@H](NC(=S)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O

InChI Key InChIKey=RIXMIOPSNNGXFZ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022747   

TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022747(CHEMBL68979 | CHEMBL304141 | 2-(3-Amino-2-hydroxy-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022747(CHEMBL68979 | CHEMBL304141 | 2-(3-Amino-2-hydroxy-...)
Affinity DataKi:  330nMAssay Description:Inhibitory activity against Leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetAminopeptidase B(Rat)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022747(CHEMBL68979 | CHEMBL304141 | 2-(3-Amino-2-hydroxy-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against aminopeptidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022747(CHEMBL68979 | CHEMBL304141 | 2-(3-Amino-2-hydroxy-...)
Affinity DataKi:  4.03E+4nMAssay Description:Inhibitory activity against Aminopeptidase MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed