BDBM50022674 CHEMBL3298267

SMILES Cc1cn(cn1)-c1ccc(cc1)-c1cn(CC(=O)Nc2cc(nn2-c2ccccc2)C2CC2)nn1

InChI Key InChIKey=OOSFKAZKSXUEGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022674   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022674(CHEMBL3298267)
Affinity DataIC50: 60nMAssay Description:Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50022674(CHEMBL3298267)
Affinity DataIC50: 9nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed