BDBM50022540 CHEMBL3297892

SMILES Cc1cc2c(Nc3cccc(c3)C#C)nc(C)nc2o1

InChI Key InChIKey=LYSQWVNEFZTXHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50022540   

TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022540(CHEMBL3297892)
Affinity DataIC50: 16nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022540(CHEMBL3297892)
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR in human A431 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50022540(CHEMBL3297892)
Affinity DataIC50: 76nMAssay Description:Inhibition of VEGFR2 in human U251 cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed