BDBM50022375 BDBM50022873::CHEMBL348469::{1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-isopropylsulfanyl-propylcarbamoyl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)SC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=PMGSGSRYNICBHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022375   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022375({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-isopropylsul...)
Affinity DataIC50: 9nMpH: 6.0Assay Description:Inhibition of human renal renin at pH 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022375({1-[1-(1-Cyclohexylmethyl-2-hydroxy-3-isopropylsul...)
Affinity DataIC50: 9.90nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed