BDBM50022368 (1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-sulfonyl)-propylcarbamoyl]-2-hydroxy-propylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester::CHEMBL3142230

SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CS(=O)(=O)C(C)C

InChI Key InChIKey=XTEOCWMPCKJLAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022368   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022368((1-{1-[1-Cyclohexylmethyl-2-hydroxy-3-(propane-2-s...)
Affinity DataIC50: 8nMAssay Description:Evaluated in vitro for inhibitory potency against renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed