BDBM50022221 2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-carboxylic acid::CHEMBL46571

SMILES Cc1c(Cn2ccnc2)n(C)c2ccc(cc12)C(O)=O

InChI Key InChIKey=MMLBTGWLFUJNGP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022221   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: 32nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: 32nMAssay Description:Compound was tested for the ability to inhibit human platelets microsomal Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against thromboxane A2 synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50022221(2-Imidazol-1-ylmethyl-1,3-dimethyl-1H-indole-5-car...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed