BDBM50022216 2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5-carboxylic acid::CHEMBL43141

SMILES Cc1c(Cn2ccnc2)sc2ccc(cc12)C(O)=O

InChI Key InChIKey=FFCLQMGMGYVLJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022216   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 17nMAssay Description:Inhibition of thromboxane TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat adrenal 11-beta-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine aorta prostacyclin PGI-2 synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50022216(2-Imidazol-1-ylmethyl-3-methyl-benzo[b]thiophene-5...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cyclooxygenase from RBL-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed