BDBM50021981 CHEMBL3297865

SMILES COc1ccc(cc1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=UXQGJOGBIHMDHQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50021981   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50: 1.20E+4nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50: 1.27E+4nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50: 1.22E+4nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 60 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50: 8.60E+3nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed