BDBM50021822 CHEMBL3298322

SMILES COc1cc2ccnc(Oc3ccc(F)cc3)c2cc1OC

InChI Key InChIKey=AHHGHXFTQVZBPO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50021822   

LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293-TREx cells assessed as intracellular level after 48 of 72 hrs by Fluo-4 NW staining-based fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293-TREx cells assessed as intracellular level after 48 of 72 hrs by Fluo-4 NW staining-based fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS/competitive screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS/competitive screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS/competitive screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS/competitive screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50021822(CHEMBL3298322)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS/competitive screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed