BDBM50021819 CHEMBL3298828

SMILES COc1nc2sc(C(=O)NCCCCCCN3CCC(CC3)c3ccc(Cl)cc3)c(N)c2c(C)c1Cl

InChI Key InChIKey=VDABMKZNXMFUQE-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021819   

TargetD(2) dopamine receptor(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50021819(CHEMBL3298828)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]spiperone from human D2L receptor expressed in FlpIn CHO cell membrane after 3 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50021819(CHEMBL3298828)
Affinity DataEC50:  5.5nMAssay Description:Partial agonist activity at human D2L receptor expressed in FlpIn CHO cells assessed as induction of ERK1/2 phosphorylation by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed