BDBM50021652 CHEMBL3297758

SMILES OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(F)c1

InChI Key InChIKey=AFHADFMYZXZAEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021652   

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021652(CHEMBL3297758)
Affinity DataIC50: 141nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021652(CHEMBL3297758)
Affinity DataIC50: 684nMAssay Description:Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed