BDBM50021410 CHEMBL3289868

SMILES COc1cccc(c1)N(C)C(=O)c1ncc(s1)-c1cccc(C)c1

InChI Key InChIKey=HEOFCTDOHLBFLO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021410   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021410(CHEMBL3289868)
Affinity DataIC50: 296nMAssay Description:Inhibition of human placental 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021410(CHEMBL3289868)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human placental 17beta-HSD1 cytosolic fraction using tritiated estrone as substrate assessed as formation of estradiol by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021410(CHEMBL3289868)
Affinity DataIC50: 296nMAssay Description:Displacement of [3H]E2 from human placental microsomal 17beta-HSD2 after 20 mins by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50021410(CHEMBL3289868)
Affinity DataIC50: 1.87E+4nMAssay Description:Displacement of [3H]E1 from human placental cytosolic17beta-HSD1 after 10 mins by cell-free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed