BDBM50021387 CHEMBL3289585

SMILES NCCC(N1CCC(CC1)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=BEGLUOXVRUSEEJ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50021387   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021387(CHEMBL3289585)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021387(CHEMBL3289585)
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021387(CHEMBL3289585)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021387(CHEMBL3289585)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021387(CHEMBL3289585)
Affinity DataKi:  2.57E+4nMAssay Description:Displacement of NO711 from mouse GAT1 expressed in HEK293 cells by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed