BDBM50021368 CHEMBL3289292

SMILES NCCC(N1CCN(CC1)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(Cl)cc1

InChI Key InChIKey=VCPAESWTSVHRMX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50021368   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021368(CHEMBL3289292)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021368(CHEMBL3289292)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021368(CHEMBL3289292)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50021368(CHEMBL3289292)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cells assessed as decrease in [3H]GABA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed