BDBM50021224 (+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine; Dihydrochloride::(+)(cis) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine; Dihydrochloride::(-) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine; Dihydrochloride::(-)(cis) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine; Dihydrochloride::(cis) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine; Dihydrochloride::(trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine; Dihydrochloride::1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL54177

SMILES CN1CCN(CC1)C1CC(c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=MFYVODATWDJWNK-UHFFFAOYSA-N

Data  36 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50021224   

LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 530nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 230nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 230nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 630nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 11nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 200nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 120nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 120nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 32nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 910nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 32nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 910nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 910nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 10nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 7.80nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 7.70nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 120nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.5nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.30E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 340nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 1.70E+3nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 4.40nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 10nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 11nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.30nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 630nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)
Affinity DataIC50: 2.50E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed