BDBM50021214 CHEMBL300019::CHEMBL537996::[3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1-yl]-methyl-amine::[3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1-yl]-methyl-amine; hydrochloride

SMILES CNC1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SPMRKSIEUHZTAA-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50021214   

LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataIC50: 19nMAssay Description:Inhibition of noradrenaline uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataIC50: 19nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of 5-HT uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataKi:  12nMAssay Description:Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataKi:  12nMAssay Description:Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataKi:  15nMAssay Description:Displacement of from norepinephrine transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021214(CHEMBL537996 | CHEMBL300019 | [3-(3,4-Dichloro-phe...)
Affinity DataKi:  15nMAssay Description:Reuptake inhibitory activity against NE transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed