BDBM50020964 1,3-Dimethyl-8-(4-nitro-phenyl)-3,7-dihydro-purine-2,6-dione::CHEMBL416884

SMILES Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=GZKNQJOZTRVLIX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020964   

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50020964(CHEMBL416884 | 1,3-Dimethyl-8-(4-nitro-phenyl)-3,7...)
Affinity DataIC50: 8nMAssay Description:Binding affinity against adenosine A1 receptor in rat brain membrane preparations using N6-[3H]cyclohexyladenosine as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50020964(CHEMBL416884 | 1,3-Dimethyl-8-(4-nitro-phenyl)-3,7...)
Affinity DataIC50: 8nMAssay Description:Binding affinity against bovine brain adenosine A1 receptor by using N6-[3H]- cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50020964(CHEMBL416884 | 1,3-Dimethyl-8-(4-nitro-phenyl)-3,7...)
Affinity DataKi:  6.94E+3nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed