BDBM50020514 2-(Hydroxyimino-methyl)-1-methoxymethyl-3-methyl-3H-imidazol-1-ium; chloride::CHEMBL289890

SMILES COC[n+]1ccn(C)c1CN=O

InChI Key InChIKey=URAIXWSQQQZTSC-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50020514   

TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Mouse)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was tested for the binding affinity towards muscarinic acetylcholine receptor in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataIC50: 2.90E+5nMAssay Description:Concentration of the HOX that inhibits 50% of AChE (Acetylcholinesterase) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataIC50: 1.34E+5nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCholine O-acetyltransferase(Rat)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataIC50: 2.90E+5nMAssay Description:Compound was tested for the competitive inhibition of acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sri International

Curated by ChEMBL
LigandPNGBDBM50020514(CHEMBL289890 | 2-(Hydroxyimino-methyl)-1-methoxyme...)
Affinity DataKi:  4.80E+4nMAssay Description:Compound was tested for the competitive inhibition of phosphorylation of Eel acetylcholinesterase (AChE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed