BDBM50020268 (R)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::(RS)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::(S)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::CHEMBL41361

SMILES CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1

InChI Key InChIKey=NKXJTSZBOBZLTH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50020268   

TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020268((R)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 81nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020268((R)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020268((R)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 23nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020268((R)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 51nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020268((R)-1-(4-Chloro-phenyl)-3-(1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 22nMAssay Description:Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed