BDBM50020240 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL1204285::CHEMBL307717

SMILES CN1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1

InChI Key InChIKey=BOFPIRRSGDHUCZ-UHFFFAOYSA-N

Data  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50020240   

LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 780nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 45nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 32nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 97nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 88nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 180nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 630nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 22nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 110nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 57nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 6.10E+3nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 91nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020240(CHEMBL1204285 | CHEMBL307717 | 1-[6-Fluoro-3-(4-fl...)
Affinity DataIC50: 410nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed