BDBM50020180 4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL541077::CHEMBL58613

SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cccc2ccoc12

InChI Key InChIKey=HUACSDTUNPSEBC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020180   

Target5-hydroxytryptamine receptor 1A(Rat)
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020180(CHEMBL541077 | CHEMBL58613 | 4-(4-Benzofuran-7-yl-...)
Affinity DataKi:  1nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020180(CHEMBL541077 | CHEMBL58613 | 4-(4-Benzofuran-7-yl-...)
Affinity DataKi:  1.5nMAssay Description:Potency to displace [3H]- WB-4101 from alpha-1 adrenergic receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020180(CHEMBL541077 | CHEMBL58613 | 4-(4-Benzofuran-7-yl-...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020180(CHEMBL541077 | CHEMBL58613 | 4-(4-Benzofuran-7-yl-...)
Affinity DataKi:  8.20nMAssay Description:Potency to displace [3H]- Spiperone from 5-hydroxytryptamine 2 receptor in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed