BDBM50019240 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-benzamide::CHEMBL72073

SMILES CN1c2ccccc2C(=NC(NC(=O)c2ccc(Cl)cc2)C1=O)c1ccccc1

InChI Key InChIKey=FGWACVODRFNWJZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50019240   

LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 6.70E+3nMAssay Description:Tested for its activity to inhibit the binding of [125I]gastrin to gastric glands (gastrin) in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 8.30nMAssay Description:Tested for its activity to inhibit the binding of [125I]CCK-33 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 8.30nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 6.70E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 8.32nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50019240(CHEMBL72073 | 4-Chloro-N-(1-methyl-2-oxo-5-phenyl-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Tested for its activity to inhibit the binding of [125I]CCK-33 to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article