BDBM50019216 CHEMBL443009::N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-phenyl-acrylamide: 0.65H2O

SMILES Fc1ccccc1C1=NC(NC(=O)\C=C\c2ccccc2)C(=O)Nc2ccccc12

InChI Key InChIKey=UXNHLBPVNCIBGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50019216   

TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019216(CHEMBL443009 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-di...)
Affinity DataIC50: 3.80E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019216(CHEMBL443009 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-di...)
Affinity DataIC50: 11nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019216(CHEMBL443009 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-di...)
Affinity DataIC50: 5.50E+3nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed