BDBM50019208 CHEMBL137922

SMILES COc1ccc(cc1OC)-c1nc(O)c2ccccc2n1

InChI Key InChIKey=QZYGERCWCIKOGH-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50019208   

TargetBeta-glucuronidase(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50019208(CHEMBL137922)
Affinity DataIC50: 600nMAssay Description:Inhibition of beta-glucuronidase activity (unknown origin) assessed as p-nitrophenol formation after 30 mins using p-nitrophenyl-beta-D-glucuronide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
China Medical College

Curated by ChEMBL
LigandPNGBDBM50019208(CHEMBL137922)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50019208(CHEMBL137922)
Affinity DataIC50: 600nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50019208(CHEMBL137922)
Affinity DataIC50: 600nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50019208(CHEMBL137922)
Affinity DataKi:  2.81E+3nMAssay Description:Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50019208(CHEMBL137922)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed