BDBM50019168 2-(3'-Hydroxyphenyl)quinazolin-4(3H)-one (3)::CHEMBL3289110

SMILES c1ccc2c(c1)C(=O)NC(=N2)c3cccc(c3)O

InChI Key InChIKey=XMXQFRPDUIBGED-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019168   

TargetThymidine phosphorylase(Escherichia coli (strain SMS-3-5 / SECEC))
University of Karachi

LigandPNGBDBM50019168(CHEMBL3289110 | 2-(3'-Hydroxyphenyl)quinazolin...)
Affinity DataIC50: 2.95E+5nMpH: 7.0Assay Description:TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 ยต...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50019168(CHEMBL3289110 | 2-(3'-Hydroxyphenyl)quinazolin...)
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of beta-glucuronidase activity (unknown origin) assessed as p-nitrophenol formation after 30 mins using p-nitrophenyl-beta-D-glucuronide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed