BDBM50019164 CHEMBL1164165

SMILES [O-][N+](=O)c1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=PDSXUXCWTDUVSZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50019164   

TargetBeta-glucuronidase(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of beta-glucuronidase activity (unknown origin) assessed as p-nitrophenol formation after 30 mins using p-nitrophenyl-beta-D-glucuronide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 259nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Human)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50019164(CHEMBL1164165)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta level incubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed