BDBM50019141 CHEMBL3288757

SMILES CN1C(=O)CN(C1=O)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=ACNGZALWLPISRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019141   

TargetSodium/glucose cotransporter 2(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50019141(CHEMBL3288757)
Affinity DataIC50: 489nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50019141(CHEMBL3288757)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed