BDBM50019137 CHEMBL3288753

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(cc2)N2CC(=O)N(C2=O)C(c2ccccc2)(c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=XDIHVUHQAPOHKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019137   

TargetSodium/glucose cotransporter 2(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50019137(CHEMBL3288753)
Affinity DataIC50: 328nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50019137(CHEMBL3288753)
Affinity DataIC50: 6.25E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed