BDBM50019136 CHEMBL3288751

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cn2nc3c(F)cccn3c2=O)c1

InChI Key InChIKey=GDSFLODVXGSYIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019136   

TargetSodium/glucose cotransporter 2(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50019136(CHEMBL3288751)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Amri

Curated by ChEMBL
LigandPNGBDBM50019136(CHEMBL3288751)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed