BDBM50018956 CHEMBL3287405

SMILES Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl

InChI Key InChIKey=JERZBICCWPTZQV-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50018956   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human dopamine D3 receptor transiently expressed in HEK293 cells co-expressing Galphao1 after 30 mins by [35S]GTPgammaS binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human dopamine D2 short receptor transiently expressed in HEK293 cells co-expressing Galphai2 after 30 mins by [35S]GTPgammaS bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataKi:  0.320nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]-ketanserin from human 5HT2A receptor expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50018956(CHEMBL3287405)
Affinity DataKi:  930nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed