BDBM50018738 1,2,3,4,5,6,11,11b-Octahydro-4a,10,11-triaza-benzo[a]fluorene::CHEMBL345621

SMILES C1CCN2CCc3c([nH]c4ncccc34)C2C1

InChI Key InChIKey=QCUFMOWEXODOQM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018738   

TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  537nMAssay Description:Compound was evaluated for log 1/Ki at alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  540nMAssay Description:Affinity to alpha-1 adrenergic receptor by the displacement of [3H]-prazosin from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  660nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018738(CHEMBL345621 | 1,2,3,4,5,6,11,11b-Octahydro-4a,10,...)
Affinity DataKi:  661nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed