BDBM50018676 CHEMBL3291015

SMILES Oc1ccc(CN(CC#C)C(C#N)C2CCN(Cc3ccccc3)CC2)c2cccnc12

InChI Key InChIKey=YTAMOLXXEXNVLH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018676   

TargetCholinesterase(Horse)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50018676(CHEMBL3291015)
Affinity DataIC50: 3.95E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed