BDBM50018553 (+)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione::(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione::(-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione::1'-(4-Bromo-benzyl)-3-phenyl-[3,4']bipiperidinyl-2,6-dione::CHEMBL10309

SMILES Brc1ccc(CN2CCC(CC2)C2(CCC(=O)NC2=O)c2ccccc2)cc1

InChI Key InChIKey=KIBLABCMQPRMIQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50018553   

TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 610nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 9.60E+3nMAssay Description:Binding affinity to human muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Johnson & Johnson Prd

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 330nMAssay Description:Displacement of [125I]ITAC from CXCR3 in PHA/IL-2 activated human PBMC pretreated 30 mins before [125I]ITAC challenge after 1 hr by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 38nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2019
Entry Details Article
PubMed