BDBM50018458 2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL440466

SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)C(=O)c2ccccc12

InChI Key InChIKey=NTZGJPKDNJJWLR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50018458   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018458(CHEMBL440466 | 2-[4-(4-Phenyl-piperazin-1-yl)-buty...)
Affinity DataKi:  10nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018458(CHEMBL440466 | 2-[4-(4-Phenyl-piperazin-1-yl)-buty...)
Affinity DataKi:  10nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]OH-DPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018458(CHEMBL440466 | 2-[4-(4-Phenyl-piperazin-1-yl)-buty...)
Affinity DataKi:  10nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018458(CHEMBL440466 | 2-[4-(4-Phenyl-piperazin-1-yl)-buty...)
Affinity DataKi:  10nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50018458(CHEMBL440466 | 2-[4-(4-Phenyl-piperazin-1-yl)-buty...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-5-OH-DPAT from human 5-HT1AR expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed