BDBM50018452 2-[5-(4-Phenyl-piperazin-1-yl)-pentyl]-isoindole-1,3-dione::CHEMBL292204

SMILES O=C1N(CCCCCN2CCN(CC2)c2ccccc2)C(=O)c2ccccc12

InChI Key InChIKey=YRCZJVPFEIPMMN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50018452   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018452(CHEMBL292204 | 2-[5-(4-Phenyl-piperazin-1-yl)-pent...)
Affinity DataKi:  8.5nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50018452(CHEMBL292204 | 2-[5-(4-Phenyl-piperazin-1-yl)-pent...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]OH-DPAT displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50018452(CHEMBL292204 | 2-[5-(4-Phenyl-piperazin-1-yl)-pent...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]-5-OH-DPAT from human 5-HT1AR expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed