BDBM50017733 (2S,4S)-2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pentanoic acid::2-Benzyl-4-(1-carboxy-ethylcarbamoyl)-5-phenyl-pentanoic acid::CHEMBL295104

SMILES OC(=O)CCNC(=O)[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)Cc1ccccc1

InChI Key InChIKey=JUUGRNXBMBREMY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017733   

TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017733(2-Benzyl-4-(1-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 8nMAssay Description:Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetNeprilysin(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017733(2-Benzyl-4-(1-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Enkephalinase from rabbit using method 2 is determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017733(2-Benzyl-4-(1-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 1.20E+3nMAssay Description:The compound was tested for inhibition of Neutral endopeptidase by using GAAP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017733(2-Benzyl-4-(1-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 9nMAssay Description:The compound was tested in vitro for inhibition of Neutral endopeptidase by using Leu enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed