BDBM50017663 CHEMBL3288676

SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cncnc1)-c1ccccc1

InChI Key InChIKey=KDSQZTJITSCKHI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50017663   

TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50017663(CHEMBL3288676)
Affinity DataIC50: 245nMAssay Description:Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50017663(CHEMBL3288676)
Affinity DataIC50: 78nMAssay Description:Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50017663(CHEMBL3288676)
Affinity DataIC50: 245nMAssay Description:Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50017663(CHEMBL3288676)
Affinity DataIC50: 78nMAssay Description:Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed